FABP1/L-FABP Antibody [Alexa Fluor® 594]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 594

FABP1/L-FABP Antibody [Alexa Fluor® 594] Summary

• Immunogen: E. coli-derived recombinant mouse FABP1/L-FABP
  Met1-Ile127
  Accession # P12710
• Specificity: Detects human, mouse, and rat FABP1/L-FABP in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FABP1/L-FABP Antibody [Alexa Fluor® 594]

• FABP1
• FABPL
• fatty acid binding protein 1, liver
• fatty acid-binding protein, liver
• LFABP
• L-FABP
• L-FABPFatty acid-binding protein 1
• Liver-type fatty acid-binding protein

Background

FABP1 (fatty acid binding protein-1; also Liver-type fatty acid binding protein/L-FABP and 14 kDa Selenium-binding protein) is a 14-15 kDa intracellular member of the fatty acid binding protein family, calycin superfamily of molecules. It is expressed by intestinal epithelium and hepatocytes, and is known to bind both cholesterol and long-chain fatty acids in the cytosol. As fatty acids diffuse across the plasma membrane, they are sequestered by FABP1, facilitating fatty acid diffusion into the cell. FABP1 also binds bile acids and cholesterol, and transports cholesterol from one membrane compartment to another. Mouse FABP1 is 127 amino acids (aa) in length. It is a two beta -sheet molecule that contains an acetylated initiating methionine. Full-length mouse FABP1 shares 94% and 84% aa identity with rat and human FABP1, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.