F4/80 Antibody (521204) [Phycoerythrin]

• Applications: Flow
• Clone: 521204
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Phycoerythrin

F4/80 Antibody (521204) [Phycoerythrin] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with mouse F4/80/EMR1
  Gln28-Gly931
  Accession # Q61549
• Specificity: Detects mouse F4/80/EMR1.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: EMR1
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

F4/80, also known as EMR1 in humans, is a 160 kDa glycosylated protein that belongs to the EGF-TM7 family of adhesion molecules. It is expressed on splenic red pulp and bone marrow, macrophages, microglia, Langerhans cells, monocytes, eosinophils, and CD116⁺ dendritic cells in mouse, but is restricted to eosinophils in human. F4/80 plays a role in the development of peripheral tolerance, being necessary for the development of CD8⁺ T regs. It also serves as a marker for IL-1 beta ⁺ proinflammatory macrophages.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for F4/80 Antibody (FAB5580P). (Showing 1 - 3 of 3 FAQ).

1. Are the F4/80/EMR1 antibodies validated in Simple Western?
   • No, F4/80/EMR1 antibodies are not tested in Simple Western at this moment.
2. Does F4/80/EMR1 antibodies come in lyophilized form?
   • Yes, we carry 2 F4/80 antibodies in lyophilized form: MAB5580 and NBP1-06975
3. What is the theoretical molecular weight for F4/80/EMR1 antibodies?
   • The TMW of F4/80/EMR1 antibodies is approximately 160 kDa.

Bioinformatics

• Gene Symbol: EMR1