EVER2 Antibody

Images

 
Western Blot: EVER2 Antibody [NBP1-76903] - Jurkat cell lysate with EVER2 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: EVER2 Antibody [NBP1-76903] - Human Brain cells.
Immunohistochemistry-Paraffin: EVER2 Antibody [NBP1-76903] - Human brain with EVER2 antibody at 5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

EVER2 Antibody Summary

Immunogen
Antibody was raised against a 14 amino acid synthetic peptide from near the center of human EVER2. The immunogen is located within amino acids 300 - 350 of EVER2.
Specificity
At least three isoforms of EVER2 are known to exist; this antibody will only recognize the larger isoform. EVER2 has no cross-reactivity to EVER1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMC8
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/mL
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
EVER2 Peptide (NBP1-76903PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for EVER2 Antibody

  • epidermodysplasia verruciformis 2
  • Epidermodysplasia verruciformis protein 2
  • EV2
  • EVER2MGC102701
  • EVIN2FLJ43684
  • FLJ40668
  • MGC40121
  • transmembrane channel-like 8
  • transmembrane channel-like protein 8

Background

Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc. At least three isoforms of EVER2 are known to exist; this antibody will only recognize the larger isoform. EVER2 has no cross-reactivity to EVER1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for EVER2 Antibody (NBP1-76903) (0)

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Secondary Antibodies

 

Isotype Controls

Additional EVER2 Products

EVER2 NBP1-76903

Bioinformatics Tool for EVER2 Antibody (NBP1-76903)

Discover related pathways, diseases and genes to EVER2 Antibody (NBP1-76903). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for EVER2 Antibody (NBP1-76903)

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Pathways for EVER2 Antibody (NBP1-76903)

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Bioinformatics

Gene Symbol TMC8
Uniprot