ETV6/Tel Antibody (3B10)

Images

 
Western Blot: ETV6/Tel Antibody (3B10) [H00002120-M01] - ETV6 monoclonal antibody (M01), clone 3B10 Analysis of ETV6 expression in Jurkat.
Immunohistochemistry-Paraffin: ETV6/Tel Antibody (3B10) [H00002120-M01] - Analysis of monoclonal antibody to ETV6 on formalin-fixed paraffin-embedded human placenta. Antibody concentration 3 ug/ml.
Sandwich ELISA: ETV6/Tel Antibody (3B10) [H00002120-M01] - Detection limit for recombinant GST tagged ETV6 is approximately 0.1ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC-P
Clone
3B10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

ETV6/Tel Antibody (3B10) Summary

Immunogen
ETV6 (AAH43399, 1 a.a. - 452 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSETPAQCSIKQERISYTPPESPVPSYASSTPLHVPVPRALRMEEDSIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQRKPRILFSPFFHPGNSIHTQPEVILHQNHEEDNCVQRTPRPSVDNVHHNPPTIELLHRSRSPITTNHRPSPDPEQRPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYPLSVSPMENNHCPASSESHPKPSSPRQESTRVIQLMPSPIMHPLILNPRHSVDFKQSRLSEDGLHREGKPINLSHREDLAYMNHIMVSVSPPEEHAMPIGRIADCRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIMSGRTDRLEHLESQELDEQIYQEDEC
Localization
Nuclear
Specificity
ETV6 - ets variant gene 6 (TEL oncogene)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ETV6
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunohistochemistry-Paraffin
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IHC-P and ELISA.
Publications
Read Publications using H00002120-M01.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ETV6/Tel Antibody (3B10)

  • ETS translocation variant 6
  • ets variant 6
  • ets variant gene 6 (TEL oncogene)
  • ETS-related protein Tel1
  • ETV6
  • TEL
  • TEL/ABL
  • TEL1
  • TELTEL1 oncogene
  • transcription factor ETV6

Background

Tel encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N terminal pointed (PNT) domain that is involved in the protein protein interactions with itself and other proteins, and a C terminal DNA binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ETV6/Tel Antibody (H00002120-M01)(2)

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Bioinformatics

Gene Symbol ETV6
Entrez
OMIM
Uniprot