Erythropoietin R Antibody (38421) [Allophycocyanin]

TF-1 human erythroleukemic cell line was stained with Mouse Anti-Human Erythropoietin R APC-conjugated Monoclonal Antibody (Catalog # FAB3072A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Hu
• Applications: Flow
• Clone: 38421
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

Erythropoietin R Antibody (38421) [Allophycocyanin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Erythropoietin R
  Ala25-Pro250
  Accession # P19235
• Specificity: Detects human Epo R in ELISAs. In ELISAs, no cross-reactivity or interference was observed with recombinant human (rh) Epo, rhTpo R, or rmEpo R.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: EPOR
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Erythropoietin R Antibody (38421) [Allophycocyanin]

• EpoR
• EPO-R
• Erythropoietin R
• erythropoietin receptor
• MGC138358

Background

Epo R is a transmembrane protein expressed on the surface of megakaryocytes, erythroid progenitors, and endothelial cells. It binds Epo and transmits signals that stimulate the proliferation and maturation of bone marrow erythroid precursors into red cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Erythropoietin R Antibody (FAB3072A)(2)

Publications using FAB3072A

• S Tarantini, MN Valcarcel-, P Toth, A Yabluchans, Z Tucsek, T Kiss, P Hertelendy, M Kinter, P Ballabh, Z Süle, E Farkas, JA Baur, DA Sinclair, A Csiszar, Z Ungvari Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice Redox Biol, 2019-04-10;24(0):101192. 2019-04-10 [PMID: 31015147] (Flow Cytometry, Rat)
• Ilaria Iacobucci, Yongjin Li, Kathryn G. Roberts, Stephanie M. Dobson, Jaeseung C. Kim, Debbie Payne-Turner et al. Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia Cancer Cell 2/8/2016 [PMID: 26859458]

Bioinformatics

• Gene Symbol: EPOR
• Uniprot:
  • P19235()