Human ERAB ELISA Kit (Colorimetric)

ELISA: Human ERAB ELISA Kit (Colorimetric) [NBP2-76588] - Samples were spiked with high concentrations of Human ERAB and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human ERAB ELISA Kit (Colorimetric) [NBP2-76588] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 25 - 1600pg/mL
• Sensitivity: 15pg/mL

Human ERAB ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human HSD17B10 in samples. No significant cross-reactivity or interference between Human HSD17B10 and analogues was observed.
• Standard Curve Range: 25 - 1600pg/mL
• Sensitivity: 15pg/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 5.27
• Intra-Assay: CV% < 5.31
• Spike Recovery: 86-109%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: HSD17B10

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human ERAB ELISA Kit (Colorimetric)

• 17-beta-HSD 10
• 17-beta-hydroxysteroid dehydrogenase 10
• 17b-HSD10
• 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
• ABAD
• amyloid-beta peptide binding alcohol dehydrogenase
• CAMR
• DUPXp11.22
• EC 1.1.1.178
• EC 1.1.1.35
• Endoplasmic reticulum-associated amyloid beta-peptide-binding protein
• ERAB3-hydroxyacyl-CoA dehydrogenase type-2
• HADH2AB-binding alcohol dehydrogenase
• hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme Adehydrogenase, type II
• hydroxysteroid (17-beta) dehydrogenase 10
• mental retardation, X-linked, syndromic 10
• MHBD
• Mitochondrial ribonuclease P protein 2,3-hydroxyacyl-CoA dehydrogenase type II
• Mitochondrial RNase P protein 2
• MRPP2HCD2
• MRX17
• MRX31
• MRXS10
• SCHAD
• SDR5C1
• short chain dehydrogenase/reductase family 5C, member 1
• short chain L-3-hydroxyacyl-CoA dehydrogenase type 2
• short chain type dehydrogenase/reductase XH98G2
• Short-chain type dehydrogenase/reductase XH98G2
• Type II HADH
• XH98G2

Background

ERAB encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: HSD17B10