Western Blot: ERAB Antibody [NB300-887] - Analysis of ERAB / HADH2 in Human Brain lysate (RIPA buffer, 30ug total protein per lane) using this antibody at 0.3ug/ml. Primary incubated for 1 hour. Detected by western blot ...read more
WB: Approx. 25 kDa band observed in human brain lysates (calculated MW of 26.9 kDa band according to NP_004484). A minor band of unknown identity was also consistently observed at appr 38 kDa. This band was successfully blocked by incubation with the immunizing peptide.
Endoplasmic reticulum-associated amyloid beta-peptide-binding protein
ERAB3-hydroxyacyl-CoA dehydrogenase type-2
HADH2AB-binding alcohol dehydrogenase
hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme Adehydrogenase, type II
hydroxysteroid (17-beta) dehydrogenase 10
mental retardation, X-linked, syndromic 10
Mitochondrial ribonuclease P protein 2,3-hydroxyacyl-CoA dehydrogenase type II
Mitochondrial RNase P protein 2
short chain dehydrogenase/reductase family 5C, member 1
short chain L-3-hydroxyacyl-CoA dehydrogenase type 2
short chain type dehydrogenase/reductase XH98G2
Short-chain type dehydrogenase/reductase XH98G2
Type II HADH
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.