EpCAM/TROP1 Antibody (PAN-EpCAM (Cocktail)) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC, IHC-P, ICC/IF
Clone
PAN-EpCAM (Cocktail)
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

EpCAM/TROP1 Antibody (PAN-EpCAM (Cocktail)) [DyLight 594] Summary

Immunogen
Recombinant human Ep-CAM protein (full-length and fragments)
Localization
Cell surface
Marker
Epithelial Marker
Specificity
It is a cocktail of four highly specific monoclonal antibodies (EGP40/826, EGP40/837, EGP40/1110, EGP40/1120) that recognize extracellular as well as intracellular domains of the epithelial cellular adhesion molecule (Ep-CAM). It is a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or Ep-CAM. Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
EPCAM
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for EpCAM/TROP1 Antibody (PAN-EpCAM (Cocktail)) [DyLight 594]

  • 17-1A
  • 323/A3
  • ACSTD1
  • antigen identified by monoclonal AUA1
  • CD326 antigen
  • CD326
  • Cell surface glycoprotein Trop-1
  • chromosome 4, surface marker (35kD glycoprotein)
  • DIAR5
  • EGP
  • EGP-2
  • EGP314
  • EGP40
  • EpCAM
  • epithelial cell adhesion molecule
  • Epithelial cell surface antigen
  • Epithelial glycoprotein 314
  • Epithelial glycoprotein
  • ESA
  • GA733-2
  • GA733-2EGP34
  • gp40
  • hEGP314
  • HNPCC8
  • KS 1/4 antigen
  • KS1/4
  • KSAHEA125
  • M1S2
  • M4S1
  • M4S1Ly74
  • Major gastrointestinal tumor-associated protein GA733-2
  • MIC18MH99
  • MOC31
  • TACST-1
  • TACSTD1
  • TROP1
  • TROP1CD326
  • Tumor-associated calcium signal transducer 1CO-17A

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for EpCAM/TROP1 Antibody (NBP2-47878DL594). (Showing 1 - 1 of 1 FAQ).

  1. I'm looking for EpCAM antibody for rat. Do you have any antibody which can use FACS?
    • We unfortunately do not have any EpCAM antibodies validated in FACS for detection of the rat protein. I am sorry for any inconvenience. I do have three products to EpCAM that can detect the rat protein. These products have been validated to detect the native rat protein, so they may work for FACS however they have not yet been tested in that particular application. If you would like to try them in your experiment you would qualify for our Innovator's Reward Program. This program was designed to help scientists with the cost of their antibodies in return for valuable information. If you decide to test an antibody in a previously untested species or application we will issue you a credit for the purchase price of the antibody in exchange for a review of your experiment using our product.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47878AF350
Alexa Fluor 405 NBP2-47878AF405
Alexa Fluor 488 NBP2-47878AF488
Alexa Fluor 532 NBP2-47878AF532
Alexa Fluor 594 NBP2-47878AF594
Alexa Fluor 647 NBP2-47878AF647
Alexa Fluor 700 NBP2-47878AF700
Alexa Fluor 750 NBP2-47878AF750
Allophycocyanin NBP2-47878APC
Allophycocyanin/Cy7 NBP2-47878APCCY7
Biotin NBP2-47878B
DyLight 350 NBP2-47878UV
DyLight 405 NBP2-47878V
DyLight 488 NBP2-47878G
DyLight 550 NBP2-47878R
DyLight 594 NBP2-47878DL594
DyLight 650 NBP2-47878C
DyLight 680 NBP2-47878FR
DyLight 755 NBP2-47878IR
FITC NBP2-47878F
HRP NBP2-47878H
Janelia Fluor 549 NBP2-47878JF549
Janelia Fluor 646 NBP2-47878JF646
PE NBP2-47878PE
PE/Atto594 NBP2-47878PEATT594
PE/Cy5.5 NBP2-47878PECY55
PE/Cy7 NBP2-47878PECY7
PerCP NBP2-47878PCP

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Bioinformatics Tool for EpCAM/TROP1 Antibody (NBP2-47878DL594)

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Diseases for EpCAM/TROP1 Antibody (NBP2-47878DL594)

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PTMs for EpCAM/TROP1 Antibody (NBP2-47878DL594)

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Research Areas for EpCAM/TROP1 Antibody (NBP2-47878DL594)

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Blogs on EpCAM/TROP1.

Stemness is responsible for onset and metastasis of colorectal cancer
By Jamshed Arslan, Pharm. D., PhD. Colorectal cancer stem cells are a rare subpopulation of colorectal cancer cells that can self-renew and initiate and sustain tumor growth when transplanted into an animal host.1,2 C...  Read full blog post.

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Bioinformatics

Gene Symbol EPCAM