ENPP-3/CD203c Antibody (NP4D6) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Clone: NP4D6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

ENPP-3/CD203c Antibody (NP4D6) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human ENPP‑3/CD203c.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ENPP-3/CD203c Antibody (NP4D6) [Alexa Fluor™ Plus 647]

• B10
• CD203c antigen
• CD203c
• dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)
• dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)
• ectonucleotide pyrophosphatase/phosphodiesterase 3
• ectonucleotide pyrophosphatase/phosphodiesterase family member 3
• E-NPP 3
• ENPP3
• ENPP-3
• gp130RB13-6
• NPP3
• PD-IBETA
• PDNP3
• PDNP3B10
• Phosphodiesterase I beta
• Phosphodiesterase I/nucleotide pyrophosphatase 3
• phosphodiesterase-I beta

Background

CD203c is a 150 kDa type II transmembrane glycoprotein with a short cytoplasmic tail. CD203c is also known as ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP-3) and modulates purinergic signaling by hydrolysis of nucleotide triphosphates. CD203c is expressed on activated basophils and mast cells during allergic reactions, cardiac muscle, hepatocytes, and epithelial cells. It is upregulated in colon and bile duct carcinomas. Within the ECD, human CD203c shares 81% aa sequence identity with mouse and rat CD203.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.