eIF4E Antibody (299910) [Alexa Fluor® 750]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, KO
• Clone: 299910
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

eIF4E Antibody (299910) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human eIF4E
  Met1-Val217
  Accession # P06730
• Specificity: Detects human, mouse and rat eIF4E.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Knockout Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for eIF4E Antibody (299910) [Alexa Fluor® 750]

• CBP
• eIF4E
• eIF-4E
• EIF4E1
• EIF4EL1
• EIF4EL1MGC111573
• eIF-4F 25 kDa subunit
• EIF4F
• eukaryotic translation initiation factor 4E
• eukaryotic translation initiation factor 4E-like 1
• mRNA cap-binding protein

Background

eIF4E (eukaryotic initiation factor 4E) interacts with the 7-methyl-GTP cap structure to facilitate the initiation and rate of translation of mRNA. Together with eIF4G and eIF4A, it forms the eIF4F complex. eIF4E activity has been shown to play a role in cell cycle progression, tumorigenesis, embryonic development, nuclear export and synaptic plasticity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.