eIF4E Products

Antibodies
eIF4E [p Ser209] Antibody
eIF4E [p Ser209] Antibody
NB100-81898
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
eIF4E Antibody (5D11)
eIF4E Antibody (5D11)
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
eIF4E Antibody (299910) [Unco ...
eIF4E Antibody (299910) [Unconjuga...
MAB3228
Species: Hu, Mu, Rt
Applications: WB, ICC
Host: Mouse Monoclonal
Lysates
eIF4E Overexpression Lysate ( ...
eIF4E Overexpression Lysate (Denat...
H00001977-T01
Species: Hu
Applications: WB
eIF4E Overexpression Lysate ( ...
eIF4E Overexpression Lysate (Native)
NBL1-10204
Applications: WB
Proteins
eIF4E Recombinant Protein
eIF4E Recombinant Protein
NBP1-45314
Species: Hu
Applications: PAGE
RNAi
eIF4E RNAi
eIF4E RNAi
H00001977-R01
Species: Hu

Description

eIF-4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It exists in two forms: as a free form (25 kDa) and as part of a multiprotein complex eIF-4F (1). eIF-4E appears to be the least abundant of the initiation factors and acts as a rate-limiting step of initiation (2). Since translation is regulated by phosphorylation, eIF-4E phosphorylation at Ser 209 by MAPK signal-integrating kinase 1 (Mnk1) and kinase 2 (Mnk2) may directly regulate the rate of protein synthesis initiation (3). There is also evidence that eIF-4E can function as an oncogene (4-5).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 1977
Alternate Names
  • eIF4E
  • mRNA cap-binding protein
  • eukaryotic translation initiation factor 4E-like 1
  • eIF-4F 25 kDa subunit
  • eIF-4E
  • EIF4F
  • EIF4E1
  • EIF4EL1MGC111573
  • CBP
  • eukaryotic translation initiation factor 4E

Research Areas for eIF4E

Find related products by research area and learn more about each of the different research areas below.

Cancer
DNA Repair
DNA replication, Transcription, Translation and Splicing
mTOR Pathway
Phospho-Specific

Bioinformatics Tool for eIF4E

Discover related pathways, diseases and genes to eIF4E. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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