Independent Antibodies: Western Blot: EIF3G Antibody [NB100-93298] - Detection of human eIF3G/EIF3S4 by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for ...read more
The immunogen recognized by this antibody maps to a region between residue 175 and 225 of human eukaryotic translation initiation factor 3, subunit G (eukaryotic translation initiation factor 3, subunit 4) using the numbering given in entry NP_003746.2 (G
Rat (100%), Bovine (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
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eukaryotic translation initiation factor 3, subunit G
Eukaryotic initiation factor 3 subunit G (eIF3G) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5'-end of cellular mRNAs near the cap structure (m7GpppN). eIF3G has been shown to directly interact with AIF (apoptosis inducing factor), a protein that plays a role in caspase-independent apoptosis. AIF is able to inhibit protein synthesis via its interaction with eIF3g.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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