EIF3G Products

Description

Eukaryotic initiation factor 3 subunit G (eIF3G) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5'-end of cellular mRNAs near the cap structure (m7GpppN). eIF3G has been shown to directly interact with AIF (apoptosis inducing factor), a protein that plays a role in caspase-independent apoptosis. AIF is able to inhibit protein synthesis via its interaction with eIF3g.

Bioinformatics

Entrez	8666 Human
Uniprot	AAH00733 Human NM_003755 Human NP_003746.2 Human O75821 Human
Product By Gene ID	8666
Alternate Names	eIF3 p42 eIF3 p44 eIF-3-delta eIF3-delta eIF3g EIF3-P42 eIF3-p44 EIF3S4eIF-3 RNA-binding subunit Eukaryotic translation initiation factor 3 RNA-binding subunit Eukaryotic translation initiation factor 3 subunit 4 eukaryotic translation initiation factor 3 subunit G eukaryotic translation initiation factor 3 subunit p42 eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD) eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa eukaryotic translation initiation factor 3, subunit G