EDNRB/Endothelin R Type B Antibody

Images

 
Western Blot: EDNRB/Endothelin R Type B Antibody [NBP1-31108] - A. A375 whole cell lysate/extract
Immunohistochemistry-Paraffin: EDNRB/Endothelin R Type B Antibody [NBP1-31108] - Paraffin-embedded Gingiva, using antibody at 1:100 dilution.
Western Blot: EDNRB/Endothelin R Type B Antibody [NBP1-31108] - A431.
Western Blot: EDNRB/Endothelin R Type B Antibody [NBP1-31108] - Rat 2 whole cell lysate/extract.

Product Details

Summary
Reactivity Hu, Rt, Bv, Mu, Po, Ca, Ch, RbSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

EDNRB/Endothelin R Type B Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Endothelin B Receptor. The exact sequence is proprietary.
Localization
Cell membrane
Predicted Species
Mouse (100%), Porcine (100%), Rabbit (100%), Canine (100%), Chicken (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EDNRB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NBP1-31108 in the following applications:

Reactivity Notes

Bovine reactivity reported in scientific literature (PMID: 26980806).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for EDNRB/Endothelin R Type B Antibody

  • ABCDS
  • EDNRB
  • endothelin B receptor
  • Endothelin receptor non-selective type
  • endothelin receptor type B
  • ETB
  • ET-B
  • ETBR
  • ET-BR
  • ETRB
  • HSCR
  • HSCR2
  • WS4A

Background

The Endothelin Receptor ETB is expressed in most tissues. Mutations of the receptor gene are responsible for Hirschsprung disease type 2, a multigenic disorder with phenotypes such as bicolored irides, megacolon, hypopigmentation, and hearing loss. The ETB receptor has similar affinity for all three endothelins and activates a phosphatidylinositol-calcium second messenger system. A splice variant, termed SVR, has been described; the sequence of the ETB-SVR receptor is identical to ET-B receptor, with the exception of the intracellular C-terminal domain. While both splice variants bind endothelin ET1, they exhibit different responses, which suggests that they may be functionally distinct. The endothelin B receptor has been reported to be expressed in adrenal, aorta, artery, brain, breast, eye, epididymis, ganglion, heart, kidney, liver, lung, ovary, placenta, prostate, skin, testis, uterus, and vessel. ESTs have been isolated from amnion, B-cell/lung/testis, breast, brain, colon, ear, embryo, eye, heart, kidney, liver, liver/spleen, lung, lymph node, placenta, prostate, and skin libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for EDNRB/Endothelin R Type B Antibody (NBP1-31108)(1)

We have publications tested in 1 confirmed species: Bovine.

We have publications tested in 1 application: IHC-P.


Filter By Application
IHC-P
(1)
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Bovine
(1)
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Bioinformatics Tool for EDNRB/Endothelin R Type B Antibody (NBP1-31108)

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Diseases for EDNRB/Endothelin R Type B Antibody (NBP1-31108)

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Bioinformatics

Gene Symbol EDNRB
Entrez
Uniprot