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Dtk/TYRO3 Antibody

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Product Details

Summary
Product Discontinued
View other related Dtk/TYRO3 Primary Antibodies

Order Details


    • Catalog Number
      NB100-2311
    • Availability
      Product Discontinued

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Dtk/TYRO3 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 850 and the C-terminus (residue 890) of human Tyro3 Tyrosine Kinase using the numbering given in Swiss-Prot entry Q06418 (GeneID 7301).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TYRO3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 5-20 ug/mg lysate
  • Western Blot 1:5000-1:20000
Application Notes
Prepare working dilution immediately before use.
Theoretical MW
97 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
Dtk/TYRO3 Overexpression Lysate

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Dtk/TYRO3 Antibody

  • Brt
  • BYK
  • Dtk
  • EC 2.7.10
  • EC 2.7.10.1
  • FLJ16467
  • Rse
  • Sky
  • Tif
  • TYRO3 protein tyrosine kinase
  • Tyro3
  • Tyrosine-protein kinase byk
  • Tyrosine-protein kinase DTK
  • tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase RSE
  • Tyrosine-protein kinase SKY

Background

Receptor protein tyrosine kinases (RPTKs) are a class of transmembrane signaling molecules. They have been shown to regulate signaling cascades that control synaptic function in the central nervous system (CNS). Tyro3 is one of three RPTKs belonging to the Axl/UFO subfamily, that also includes Axl and Mer. Tyro3 is the most commonly expressed of these receptors in the CNS. It may be involved in the cell adhesion process, and is commonly found in adult tissues with expression mostly in brain, testis, vascular and lymphatic tissue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Control Lysate(s)

Dtk/TYRO3 Overexpression Lysate

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TYRO3
Entrez
Uniprot