DR1 Antibody - BSA Free

Western Blot: DR1 Antibody [NBP1-03329] - Whole cell lysate (5, 15 and 50 ug) from HeLa cells. Antibody used at 1 ug/ml.

• Reactivity: Hu
• Applications: WB, IP (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

DR1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit DR1 Antibody - BSA Free (NBP1-03329) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 25 and 75 of human down-regulator of transcription 1 using the numbering given in entry NP_001929.1 (GeneID 1810).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DR1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:2000-1:5000
• Application Notes: This antibody is useful for western blot. It is not recommended for immunoprecipitation.
• Control:

  DR1 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for DR1 Antibody - BSA Free

• Down-regulator of transcription 1
• down-regulator of transcription 1, TBP-binding (negative cofactor 2)
• NC2
• NC2-BETA
• Negative cofactor 2-beta
• protein Dr1
• TATA-binding protein-associated phosphoprotein

Background

DR1 encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DR1
• Entrez:
  • 1810(Human)
• Uniprot:
  • NP_001929.1(Human)