Dopamine D2 R/DRD2 was detected in immersion fixed paraffin-embedded sections of human brain (striatum) using Mouse Anti-Human Dopamine D2 R/DRD2 Monoclonal Antibody (Catalog # MAB9266) at 5 µg/mL for 1 hour at ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Dopamine D2R/DRD2 Antibody (960710) [Unconjugated]
D(2) dopamine receptor
Dopamine D2 R
Dopamine D2 receptor
dopamine receptor D2 isoform
dopamine receptor D2
seven transmembrane helix receptor
Dopamine receptor D2 (DRD2) is localized to human striatum,
motor cortex and neocortex. It is a highly conserved seven transmembrane
receptor member of the G-protein coupled receptor 1 family, with three known
isoforms. In the striatum, DRD2 suppresses voluntary activity in the
striatopallidal pathway, and polymorphisms in this gene are associated with alcohol
addiction, smoking behavior, schizophrenia, food addiction and post-traumatic stress
disorder as well as myoclonus dystonia.
DRD2 has been shown to heterodimerize with DDR4 and 5-HT2A receptors,
and traffics between the plasma membrane and intracellular pools and this
localization can be modulated by several drugs.
DRD2 is localized to human striatum, motor cortex and neocortex.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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