Reactivity | HuSpecies Glossary |
Applications | IHC |
Clone | 960710 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Immunogen | Human DRD2 synthetic peptide Accession # P14416 |
Specificity | Detects human Dopamine D2 R/DRD2 in direct ELISAs. |
Source | N/A |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
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Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. |
Dopamine receptor D2 (DRD2) is localized to human striatum, motor cortex and neocortex. It is a highly conserved seven transmembrane receptor member of the G-protein coupled receptor 1 family, with three known isoforms. In the striatum, DRD2 suppresses voluntary activity in the striatopallidal pathway, and polymorphisms in this gene are associated with alcohol addiction, smoking behavior, schizophrenia, food addiction and post-traumatic stress disorder as well as myoclonus dystonia. DRD2 has been shown to heterodimerize with DDR4 and 5-HT2A receptors, and traffics between the plasma membrane and intracellular pools and this localization can be modulated by several drugs. DRD2 is localized to human striatum, motor cortex and neocortex.
Secondary Antibodies |
Isotype Controls |
Diseases for Dopamine D2R/DRD2 Antibody (MAB9266)Discover more about diseases related to Dopamine D2R/DRD2 Antibody (MAB9266).
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PTMs for Dopamine D2R/DRD2 Antibody (MAB9266)Learn more about PTMs related to Dopamine D2R/DRD2 Antibody (MAB9266).
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