DNMT3A Antibody


Western Blot: Dnmt3a Antibody [NBP2-03985] - Analysis of Dnmt3a in transfected 293 cell lysate using NBP2-03985 at 1 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and ECL substrate solution were used for this test.

Product Details

Reactivity Hu, Mu, Bv, Ch, Eq, Fe, PmSpecies Glossary
Applications WB
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

DNMT3A Antibody Summary

A portion of amino acids 170-220 of human Dnmt3a was used as the immunogen
This antibody will not cross react with Dnmt3b.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
100 ug in 200 ul PBS containing 0.05% BSA
0.05% Sodium Azide
Immunogen affinity purified


  • Western Blot 1-3 ug/ml

Reactivity Notes

Reacts with Cat, Chicken, Chimpanzee, Cow, Horse, Human and Mouse.

Alternate Names for DNMT3A Antibody

  • DNA (cytosine-5-)-methyltransferase 3 alpha
  • DNA (cytosine-5)-methyltransferase 3A
  • DNA cytosine methyltransferase 3A2
  • DNA methyltransferase HsaIIIA
  • DNA MTase HsaIIIA
  • Dnmt3a
  • DNMT3A2
  • EC
  • M.HsaIIIA


Dnmt3a, also known as DNA (cytosine-5)-methyltransferase 3A, is a nuclear protein belonging to the C5-methyltransferase family with an ADD-type zinc finger and a PWWP domain. This nuclear protein localizes to euchromatin and is essential for genome wide de novo methylation and is also essential for development. DNA methylation is coordinated with methylation of histones. Dnmt3a associates with HDAC1 through its ADD-type zinc-finger. It binds to the ZNF238 transcriptional repressor and is also known to interact with other DNA methyltransferases like Dnmt1 and Dnmt3b


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

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Blogs on DNMT3A.

The role of DNMT3A in development
Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...  Read full blog post.

Go Ahead! Make My DNA
DNA methylation plays a critical role the long-term silencing of transcription and is essential for processes such as embryonic development, germline differentiation, and tissue maturation. Dnmt3a is a member of the C5-methyltransferase family that re...  Read full blog post.

DNMT's: An Overview of 3 DNA Methyltransferases
DNA methyltransferases catalyze the transfer of the methyl group from S-andenosyl methionine (SAM) to DNA. Such methylation has wide ranging function in the cell, including organismal development and cell differentiation. In cancer, abnormal hypermeth...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol DNMT3A

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