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DNA Ligase I Antibody (AG12)

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Product Details

Summary
Product Discontinued
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    • Catalog Number
      H00003978-M01
    • Availability
      Product Discontinued

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DNA Ligase I Antibody (AG12) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
LIG1 (NP_000225 810 a.a. - 919 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPEDTY
Specificity
LIG1 - ligase I, DNA, ATP-dependent
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
LIG1
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IHC-P and ELISA.
Publications
Read Publication using H00003978-M01.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DNA Ligase I Antibody (AG12)

  • DNA ligase 1
  • DNA Ligase I
  • EC 6.5.1.1
  • ligase I, DNA, ATP-dependent
  • MGC117397
  • MGC130025
  • Polydeoxyribonucleotide synthase [ATP] 1
  • polydeoxyribonucleotide synthase ATP 1

Background

LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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DNA Ligase I
Antibody (AG12)
H00003978-M01
DNA Ligase I Antibody (AG12)
Species: Hu
Applications: WB, ELISA, IHC

Publications for DNA Ligase I Antibody (H00003978-M01)(1)


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Secondary Antibodies

 

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Blogs on DNA Ligase I.

Check out the latest blog posts on DNA Ligase I.
Using PCNA as an Antibody Marker
PCNA antibodies are useful biomarkers in DNA repair studies. PCNA is one of several proteins essential for the completion of nucleotide excision repair, a multi-stage process involving 20 - 30 proteins, and an important factor in repairing damage and ...  Read full blog post.

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Bioinformatics

Gene Symbol LIG1
Entrez
OMIM
Uniprot