DNA Ligase I Products

Antibodies
DNA Ligase I Antibody (10H5)
DNA Ligase I Antibody (10H5)
NB100-119
Species: Hu, Mu
Applications: WB, ICC/IF, IP
Host: Mouse Monoclonal
DNA Ligase I Antibody
DNA Ligase I Antibody
NB100-56635
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
DNA Ligase I Antibody
DNA Ligase I Antibody
NB100-58815
Species: Hu, Pm
Applications: ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
DNA Ligase I Overexpression L ...
DNA Ligase I Overexpression Lysate...
NBP2-11159
Applications: WB
DNA Ligase I Overexpression L ...
DNA Ligase I Overexpression Lysate...
H00003978-T02
Species: Hu
Applications: WB
Proteins
DNA Ligase I Recombinant Prot ...
DNA Ligase I Recombinant Protein A...
NBP2-55992PEP
Species: Hu
Applications: B/N, Ctrl
Recombinant Human DNA Ligase ...
Recombinant Human DNA Ligase I Pro...
H00003978-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
DNA Ligase I RNAi
DNA Ligase I RNAi
H00003978-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

DNA ligase 1 catalyzes the joining of double-stranded DNA ends during replication, recombination, and repair. Structurally, DNA ligase 1 is toroidal and encircles nicked DNA substrates. The 9-1-1 complex, a DNA damage checkpoint complex, has been reported to associate with DNA ligase 1 and stimulate ligase activity. Mutations in DNA ligase 1 result in immunodeficiency and increased sensitivity to DNA-damaging agents.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Human
Product By Gene ID 3978
Alternate Names
  • DNA ligase I
  • MGC117397
  • polydeoxyribonucleotide synthase ATP 1
  • EC 6.5.1.1
  • DNA ligase 1
  • Polydeoxyribonucleotide synthase [ATP] 1
  • MGC130025
  • ligase I, DNA, ATP-dependent

Research Areas for DNA Ligase I

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Base Excision Repair
Cancer
DNA Repair
Nucleotide Excision Repair
Tumor Suppressors

PTMs for DNA Ligase I

Learn more about PTMs related to DNA Ligase I.

Phosphorylation
Cleavage
Biotinylation
Methylation

Bioinformatics Tool for DNA Ligase I

Discover related pathways, diseases and genes to DNA Ligase I. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related DNA Ligase I Blog Posts

Check out the latest blog posts on DNA Ligase I.
Using PCNA as an Antibody Marker
PCNA antibodies are useful biomarkers in DNA repair studies. PCNA is one of several proteins essential for the completion of nucleotide excision repair, a multi-stage process involving 20 - 30 proteins, and an important factor in repairing damage and...    Read more.
Read more DNA Ligase I related blogs.