DMBT1/GP340 Antibody (5D7) - BSA Free

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody (5D7) - BSA Free [NBP1-05148] - Localization of gp-340 by immunohistochemical staining of paraffin embedded section of human lung with a streptavidin biotin immunocytochemical technique. The immunoreaction product, stained with NBP1-05148, is red and the section was counterstained with Mayers hematoxylin.

Product Discontinued

DMBT1/GP340 Antibody (5D7) - BSA Free Summary

• Immunogen: Native gp-340 purified from bronchioaveolar lavage from proteinosis patients
• Specificity: Specific for gp-340, but reacts with a carbohydrate epitope and cross-reacts with saliva MUC7 in immunohistochemistry.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: DMBT1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:60000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:200-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 10mM Phosphate (pH 7.4) and 0.5M NaCl
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for DMBT1/GP340 Antibody (5D7) - BSA Free

• CRP-ductin
• deleted in malignant brain tumors 1 protein
• deleted in malignant brain tumors 1
• DMBT1
• Ebnerin
• FLJ61058
• Glycoprotein 340
• GP340
• gp-340
• GP340muclin
• Hensin
• MGC164738
• Muclin
• SAG
• Salivary agglutinin
• Surfactant pulmonary-associated D-binding protein
• Vomeroglandin

Background

Glycoprotein-340 is member of the scavenger receptor superfamily and has been identified as a putative SP-D receptor. Gp-340 has been shown to bind SP-D in a calcium dependent manner through a protein-protein interaction. Like SP-D, gp-340 is mainly found in lung tissue and immunohistochemistry revealed high expression in alveolar macrophages (1). An identical protein is present in saliva (salivary agglutinin) and both forms are encoded by the gene DMBT1 (5).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DMBT1