DLC1 Antibody

Western Blot: DLC1 Antibody [NBP2-16173] - Sample (30 ug of whole cell lysate) A: HepG2 5% SDS PAGEdiluted at 1:1000

Immunohistochemistry-Paraffin: DLC1 Antibody [NBP2-16173] - Human breast cancer, using DLC1 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

• Reactivity: Hu, Mu, Rt, Bv, Ca
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

DLC1 Antibody Summary

• Description: Novus Biologicals Rabbit DLC1 Antibody (NBP2-16173) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human DLC1. The exact sequence is proprietary.
• Localization: Cytoplasm
• Predicted Species: Rat (93%), Canine (97%), Bovine (96%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DLC1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 171 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for DLC1 Antibody

• ARHGAP7 STARD12 deleted in liver cancer 1 variant 2
• Deleted in liver cancer 1 protein
• deleted in liver cancer 1
• DLC-1
• FLJ21120
• HP protein
• HP
• KIAA1723
• p122-RhoGAP
• rho GTPase-activating protein 7
• Rho-GTPase-activating protein 7
• Rho-type GTPase-activating protein 7
• StARD12
• StAR-related lipid transfer (START) domain containing 12
• StAR-related lipid transfer protein 12
• START domain-containing protein 12

Background

This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. Alternative splicing at this locus results in several transcript variants encoding different isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: DLC1
• Uniprot:
  • Q96QB1(Human)