DIO3 Antibody [DyLight 550]


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Product Details

Reactivity Hu, Mu, Rt, HaSpecies Glossary
Applications WB
Please see the vial label for concentration. If unlisted please contact technical services.

DIO3 Antibody [DyLight 550] Summary

Synthetic peptide made to an internal portion of rat DIO3 (within residues 1-100). [Swiss-Prot# P49897]
Cell membrane; Single-pass type II membrane protein
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 550
DyLight 550 (A=562, E=576)
50mM Sodium Borate
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified


Application Notes
This DIO3 antibody is useful for Immunocytochemistry/Immunofluorescence (PMID: 21828183) and Western blot, where a band is seen ~31 kDa

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
31 kDa

Reactivity Notes

Human, rat, mouse and hamster. Human reactivity was confirmed in PMID 22723689.

Alternate Names for DIO3 Antibody [DyLight 550]

  • 5DIII
  • D3
  • deiodinase, iodothyronine, type III
  • EC 1.97.1
  • EC
  • ITDI3
  • placental type
  • thyroxine deiodinase type III (selenoprotein)
  • Type 3 DI
  • type 3 iodothyronine selenodeiodinase
  • type III iodothyronine deiodinase
  • type-III 5' deiodinase
  • Type-III 5'-deiodinase


Dio3, or type 3 iodothyronine deiodinase, can regulate circulating fetal thyroid hormone concentrations throughout gestation. It has an essential role for regulation of thyroid hormone inactivation during embryological development, and may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Dio3 has been linked to the development of consumptive hypothyroidism in both infants and adults.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for DIO3 Antibody (NB110-96414R). (Showing 1 - 1 of 1 FAQ).

  1. I am looking for a Dio3 peptide that I can inject in vivo to produce a biological effect. Can you provide information or confirm whether the Dio3 peptide you have would be effective as a biological agent in vivo?
    • I have pulled up information on the Dio3 peptides and recombinant proteins that we have available. Unfortunately I would not expect any of them to be biologically active and capable of producing a response when injected in vivo. The two peptides we carry are simply intended to be used for negative control competition assays to block signal of the primary and determine what is specific and non-specific as far as signal is concerned. The other two recombinant proteins are ones we distribute for a Taiwanese company called Abnova and they should not be biologically active based on the cell free wheat germ system employed to synthesize them. We will typically list our active proteins with an indication of such on our datasheet if it has been tested and usually the application of functional listed.

Secondary Antibodies


Isotype Controls

Other Available Formats

Biotin Labeled NB110-96414B
DyLight 488 Labeled NB110-96414G
DyLight 650 Labeled NB110-96414C
HRP Labeled NB110-96414H

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Contact Information

Product PDFs


Gene Symbol DIO3

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