DIO3 Products

Antibodies
Lysates
DIO3 Overexpression Lysate (N ...
DIO3 Overexpression Lysate (Native)
NBP2-04196
Applications: WB
Proteins
DIO3 Peptide
DIO3 Peptide
NB110-96414PEP
Species: Rt
Applications: ICC/IF
DIO3 Peptide
DIO3 Peptide
NBP1-05767PEP
Species: Rt
Recombinant Human DIO3 Protei ...
Recombinant Human DIO3 Protein
H00001735-Q01
Species: Hu
Applications: WB, ELISA, PA

Description

Iodothyronine deiodinase 3 (DIO3) is a peroxidase enzyme that is involved in the activation or deactivation of thyroid hormones. Specifically, DIO-3 deiodinizes the thyroid hormones T4 and T3 into their respective inactive metabolites, RT3 and T2.

Dio3 has an essential role for regulation of thyroid hormone inactivation during embryological development, and may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Dio3 has been linked to the development of consumptive hypothyroidism in both infants and adults.

DIO3 antibodies are useful tools for hormone regulation research and in some embryological development studies.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 1735
Alternate Names
  • EC 1.97.1
  • D3
  • ITDI3
  • EC 1.97.1.11
  • type-III 5' deiodinase
  • DIOIII
  • type III iodothyronine deiodinase
  • 5DIII
  • type 3 iodothyronine selenodeiodinase
  • Type-III 5'-deiodinase
  • thyroxine deiodinase type III (selenoprotein)
  • Type 3 DI
  • placental type
  • deiodinase, iodothyronine, type III

Research Areas for DIO3

Find related products by research area and learn more about each of the different research areas below.

Cancer
Growth and Development
Lipid and Metabolism
Neuroscience
Signal Transduction

PTMs for DIO3

Learn more about PTMs related to DIO3.

Methylation
Deiodination
Carboxylation
Cleavage
Bromination
Ubiquitination

Bioinformatics Tool for DIO3

Discover related pathways, diseases and genes to DIO3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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