delta 2 Catenin Antibody - BSA Free

Immunohistochemistry-Paraffin: delta 2 Catenin Antibody [NBP2-47487] - Staining in human cerebral cortex and pancreas tissues using anti-CTNND2 antibody. Corresponding CTNND2 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: delta 2 Catenin Antibody [NBP2-47487] - Staining of human pancreas shows low expression as expected.

Immunohistochemistry: delta 2 Catenin Antibody [NBP2-47487] - Staining of human cerebral cortex shows moderate cytoplasmic and nuclear positivity in neuronal cells, neuropil displayed moderate cytoplasmic staining.

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

delta 2 Catenin Antibody - BSA Free Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: ASQLERCKLGSETGSMSSMSSAEEQFQWQSQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDYSTGERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGETTPSQLPARGTQARATGQSFSQGTTSRA
• Predicted Species: Mouse (93%), Rat (92%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CTNND2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  delta 2 Catenin Protein (NBP2-47487PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for delta 2 Catenin Antibody - BSA Free

• catenin (cadherin-associated protein), delta 2 (neural plakophilin-relatedarm-repeat protein)
• catenin delta-2
• Delta-catenin
• GT24T-cell delta-catenin
• Neural plakophilin-related ARM-repeat protein
• Neurojungin
• NPRAPneurojungin

Background

Delta-Catenin, is a member of the p120 catenin subfamily of catenins. Delta-Catenin/NPRAP was identified as a protein homologous to plakophilin 1 and as a protein interacting with the loop region of presenilin 1 (PS1), the gene most commonly mutated in Alzheimer's disease. Delta-Catenin/NPRAP is almost exclusively expressed in the central nervous system mainly during early brain development. Delta-Catenin/NPRAP has been shown to co-localize and interact with N-cadherin in the mouse brain and to undergo dynamic relocalization during brain development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CTNND2