DEGS1 Antibody - BSA Free

Immunohistochemistry: DEGS1 Antibody [NBP3-11921] - Immunohistochemical staining of normal human brain tissue using DEGS1 antibody at 15 ug/ml.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

DEGS1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit DEGS1 Antibody - BSA Free (NBP3-11921) is a polyclonal antibody validated for use in IHC and WB. Anti-DEGS1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide derived from the human DEGS1 protein (Uniprot: O15121)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DEGS1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 10 - 15 ug/ml/ Optimal concentration should be evaluated by serial dilutions.
  • Western Blot 1:400
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris buffered saline
• Preservative: 0.08% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for DEGS1 Antibody - BSA Free

• Cell migration-inducing gene 15 protein
• Degenerative spermatocyte homolog 1
• degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)
• degenerative spermatocyte homolog, lipid desaturase (Drosophila)
• DEGS
• DEGS1
• DES1
• Des-1
• DES1degenerative spermatocyte homolog, lipid desaturase
• EC 1.14
• EC 1.14.19.17
• EC 5.2.1.-
• FADS7
• membrane fatty acid (lipid) desaturase
• Membrane lipid desaturase
• MGC5079
• MIG15
• migration-inducing gene 15 protein
• MLDdihydroceramide desaturase
• Retinol isomerase
• sphingolipid delta 4 desaturase
• sphingolipid delta(4)-desaturase DES1

Background

DEGS1 encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for DEGS1 Antibody (NBP3-11921)(1)

Publication using NBP3-11921

• Bartłomiej Łukaszuk, Elżbieta Supruniuk, Adrian Chabowski, Agnieszka Mikłosz Adipose tissue place of origin and obesity influence sphingolipid signaling pathway in the adipocytes differentiated from ADMSCs isolated from morbidly obese women. Biochemical pharmacology 2024-03-21 [PMID: 38521475]

Bioinformatics

• Gene Symbol: DEGS1
• Uniprot:
  • O15121(Human)
  • O09005(Mouse)
  • Q5XIF5(Rat)