DDX46 Antibody

Images

 
Immunohistochemistry-Paraffin: DDX46 Antibody [NB100-57489] - Human breast carcinoma (left) and mouse teratoma (right). Antibody used at a dilution of 1:1,000 (0.2ug/ml).
Independent Antibodies: Immunoprecipitation: DDX46 Antibody [NB100-57489] - Detection of Human DDX46 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
Validated by:
 

Independent Antibodies

       

Order Details

DDX46 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 300 and 350 of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 using the numbering given in entry NP_055644.2 (GeneID 9879).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DDX46
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 2 - 5 ug/mg lysate
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DDX46 Antibody

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
  • DEAD box protein 46
  • EC 3.6.1
  • EC 3.6.4.13
  • FLJ25329
  • KIAA0801probable ATP-dependent RNA helicase DDX46
  • MGC9936
  • PRP5 homolog
  • Prp5
  • Prp5-like DEAD-box protein
  • PRPF5
  • RNA helicase

Background

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DDX46
Entrez
Uniprot