DCAR/CLEC4B Antibody (349214) [Alexa Fluor™ Plus 555]

• Reactivity: Mu
• Clone: 349214
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 555

DCAR/CLEC4B Antibody (349214) [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects mouse DCAR/CLEC4B in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DCAR/CLEC4B Antibody (349214) [Alexa Fluor™ Plus 555]

• Aplra2
• CLEC4B
• CLECSF3
• DCAR
• LSLCL
• P47
• SCGF

Background

Dendritic Cell immuno-Activating Receptor alpha isoform (DCAR) is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4B. Two isoforms of DCAR exist, a 209 amino acid (aa) residue alpha isoform and a 176 aa form with a 33 aa deletion at the membrane proximal region of the extracellular domain. The DCAR extracellular domain contains a carbohydrate-recognition domain (CRD) that shares 91% amino acid sequence identity with the CRD of DCIR/CLEC4A. The DCAR intracellular domain is very short and lacks the ITIM motif found in DCIR. DCAR and DCIR are considered paired immunoregulatory receptors where DCAR activates through the ITAM of its associated adaptor molecule FcR gamma .

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.