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DCAR/CLEC4B Products

Antibodies

Description

DCAR is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4B. Two isoforms of DCAR, including the 209 amino acid (aa) residue alpha isoform and a 176 aa form with a 33 aa deletion at the membrane proximal region of the extracellular domain, exist. The DCAR extracellular domain contains a carbohydrate-recognition domain (CRD) that shares 91% amino acid sequence identity with the CRD of DCIR/CLEC4A. The DCAR intracellular domain is very short and lacks the ITIM motif found in DCIR. DCAR and DCIR are considered paired immunoregulatory receptors where DCAR activates through the ITAM of its associated adaptor molecule FcR gamma .

Bioinformatics

Uniprot
Product By Gene ID 6320
Alternate Names
  • Aplra2
  • CLEC4B
  • CLECSF3
  • DCAR
  • LSLCL
  • P47
  • SCGF

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