DAP10/HCST Antibody (982129) [Unconjugated]

Images

 
Human U937 histiocytic lymphoma cell line was stained with Mouse Anti-Human DAP10/HCST Monoclonal Antibody (Catalog # MAB9786, filled histogram) or Mouse IgG2A isotype control antibody (Catalog # MAB003, open histogram) ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications CyTOF-ready, Flow
Clone
982129
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

DAP10/HCST Antibody (982129) [Unconjugated] Summary

Immunogen
Synthetic peptide containing human DAP10/HCST
Accession # Q9UBK5
Specificity
Detects human DAP10/HCST in direct ELISAs.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DAP10/HCST Antibody (982129) [Unconjugated]

  • DAP10
  • DAP10PIK3AP
  • DKFZP586C1522
  • HCST
  • hematopoietic cell signal transducer
  • KAP10
  • KAP10DNAX-activation protein 10
  • kinase assoc pro of ~10kDa
  • Kinase Assoc Protein
  • Membrane protein DAP10
  • phosphoinositide-3-kinase adaptor protein
  • PIK3AP
  • Transmembrane adapter protein KAP10

Background

This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB9786U
Alexa Fluor 405 FAB9786V
Alexa Fluor 488 FAB9786G
Alexa Fluor 594 FAB9786T
Alexa Fluor 647 FAB9786R
Alexa Fluor 700 FAB9786N
Alexa Fluor 750 FAB9786S

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