DAP10/HCST Products

Description

This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	10870
Alternate Names	DAP10 DAP10PIK3AP DKFZP586C1522 HCST hematopoietic cell signal transducer KAP10 KAP10DNAX-activation protein 10 kinase assoc pro of ~10kDa Kinase Assoc Protein Membrane protein DAP10 phosphoinositide-3-kinase adaptor protein PIK3AP Transmembrane adapter protein KAP10

Research Areas for DAP10/HCST

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Immune System Diseases
Immunology
Innate Immunity