DAP10/HCST Antibody (982107) [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Applications: Flow, IHC
• Clone: 982107
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

DAP10/HCST Antibody (982107) [Alexa Fluor™ Plus 488] Summary

• Immunogen: Synthetic peptide containing human DAP10/HCST
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: HCST
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DAP10/HCST Antibody (982107) [Alexa Fluor™ Plus 488]

• DAP10
• DAP10PIK3AP
• DKFZP586C1522
• HCST
• hematopoietic cell signal transducer
• KAP10
• KAP10DNAX-activation protein 10
• kinase assoc pro of ~10kDa
• Kinase Assoc Protein
• Membrane protein DAP10
• phosphoinositide-3-kinase adaptor protein
• PIK3AP
• Transmembrane adapter protein KAP10

Background

HCST encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HCST