Cytokeratin 8/18 Antibody (KRT8/803 + KRT18/835) [PE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
KRT8/803 + KRT18/835
Clonality
Monoclonal
Host
Mouse
Conjugate
PE

Order Details

Cytokeratin 8/18 Antibody (KRT8/803 + KRT18/835) [PE] Summary

Immunogen
Recombinant full-length human KRT8 protein (KRT8/803); Recombinant full-length human KRT18 protein (KRT18/835)
Localization
Cytoplasmic
Specificity
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immuno-histochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
KRT8
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Cytokeratin 8/18 Antibody (KRT8/803 + KRT18/835) [PE]

  • CARD2
  • CK8
  • CK-8
  • CYK8cytokeratin 8
  • Cytokeratin-8
  • K2C8
  • K8cytokeratin-8
  • keratin 8
  • keratin, type II cytoskeletal 8
  • keratin-8
  • KO
  • Type-II keratin Kb8

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47983AF350
Alexa Fluor 405 NBP2-47983AF405
Alexa Fluor 488 NBP2-47983AF488
Alexa Fluor 532 NBP2-47983AF532
Alexa Fluor 594 NBP2-47983AF594
Alexa Fluor 647 NBP2-47983AF647
Alexa Fluor 700 NBP2-47983AF700
Alexa Fluor 750 NBP2-47983AF750
Allophycocyanin NBP2-47983APC
Biotin NBP2-47983B
DyLight 350 NBP2-47983UV
DyLight 405 NBP2-47983V
DyLight 488 NBP2-47983G
DyLight 550 NBP2-47983R
DyLight 594 NBP2-47983DL594
DyLight 650 NBP2-47983C
DyLight 680 NBP2-47983FR
DyLight 755 NBP2-47983IR
FITC NBP2-47983F
HRP NBP2-47983H
Janelia Fluor 549 NBP2-47983JF549
Janelia Fluor 646 NBP2-47983JF646
PE NBP2-47983PE
PerCP NBP2-47983PCP

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Bioinformatics Tool for Cytokeratin 8/18 Antibody (NBP2-47983PE)

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Bioinformatics

Gene Symbol KRT8
Uniprot