Reactivity | HuSpecies Glossary |
Applications | Flow |
Clone | KRT8/803 + KRT18/835 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | PE |
Immunogen | Recombinant full-length human KRT8 protein (KRT8/803); Recombinant full-length human KRT18 protein (KRT18/835) |
Localization | Cytoplasmic |
Specificity | Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immuno-histochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3. |
Isotype | IgG |
Clonality | Monoclonal |
Host | Mouse |
Gene | KRT8 |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
|
Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | PBS |
Preservative | 0.05% Sodium Azide |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | NBP2-47983AF350 | |
Alexa Fluor 405 | NBP2-47983AF405 | |
Alexa Fluor 488 | NBP2-47983AF488 | |
Alexa Fluor 532 | NBP2-47983AF532 | |
Alexa Fluor 594 | NBP2-47983AF594 | |
Alexa Fluor 647 | NBP2-47983AF647 | |
Alexa Fluor 700 | NBP2-47983AF700 | |
Alexa Fluor 750 | NBP2-47983AF750 | |
Allophycocyanin | NBP2-47983APC | |
Biotin | NBP2-47983B | |
DyLight 350 | NBP2-47983UV | |
DyLight 405 | NBP2-47983V | |
DyLight 488 | NBP2-47983G | |
DyLight 550 | NBP2-47983R | |
DyLight 594 | NBP2-47983DL594 | |
DyLight 650 | NBP2-47983C | |
DyLight 680 | NBP2-47983FR | |
DyLight 755 | NBP2-47983IR | |
FITC | NBP2-47983F | |
HRP | NBP2-47983H | |
Janelia Fluor 549 | NBP2-47983JF549 | |
Janelia Fluor 646 | NBP2-47983JF646 | |
PE | NBP2-47983PE | |
PerCP | NBP2-47983PCP |
Diseases for Cytokeratin 8/18 Antibody (NBP2-47983PE)Discover more about diseases related to Cytokeratin 8/18 Antibody (NBP2-47983PE).
| Pathways for Cytokeratin 8/18 Antibody (NBP2-47983PE)View related products by pathway.
|
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.