Cytokeratin 7 Antibody (KRT7/1499R)

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Immunohistochemistry-Paraffin: Cytokeratin 7 Antibody (KRT7/1499R) [NBP2-49880] - Human Oviduct stained with Cytokeratin 7 Rabbit Monoclonal Antibody (KRT7/1499R)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC-P, ICC/IF
Clone
KRT7/1499R
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Cytokeratin 7 Antibody (KRT7/1499R) Summary

Immunogen
Recombinant full-length human KRT7 protein
Localization
Cytoplasmic
Marker
Glandular and Transitional Epithelial Marker
Specificity
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
KRT7
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 0.5-1ug/million cells
  • Immunohistochemistry-Paraffin 0.5-1.0ug/ml
  • Immunofluorescence 0.5-1ug/ml
Application Notes
Human Chromosome Location: 12q13.13
Immunohistology (Formalin-fixed) (0.5-1.0ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10mM PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for Cytokeratin 7 Antibody (KRT7/1499R)

  • CK7
  • CK-7
  • cytokeratin 7
  • cytokeratin-7
  • K2C7
  • K7keratin, 55K type II cytoskeletal
  • keratin 7
  • keratin, type II cytoskeletal 7
  • keratin-7
  • MGC129731
  • MGC3625
  • sarcolectin
  • SCLkeratin, simple epithelial type I, K7
  • type II mesothelial keratin K7
  • Type-II keratin Kb7

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KRT7