Cytokeratin 14 Antibody (KRT14/532) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications Flow, IHC, IHC-P
Clone
KRT14/532
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405

Order Details

Cytokeratin 14 Antibody (KRT14/532) [Alexa Fluor® 405] Summary

Immunogen
Recombinant full-length human KRT14 protein
Localization
Cytoplasmic
Marker
Squamous Cell Marker
Specificity
Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
Isotype
IgG3
Clonality
Monoclonal
Host
Mouse
Gene
KRT14
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Cytokeratin 14 Antibody (KRT14/532) [Alexa Fluor® 405]

  • CK14
  • CK-14
  • Cytokeratin 14
  • cytokeratin-14
  • EBS3
  • EBS4
  • K14
  • keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)
  • keratin 14
  • keratin, type I cytoskeletal 14
  • keratin-14
  • KRT14
  • NFJ

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47720AF350
Alexa Fluor 405 NBP2-47720AF405
Alexa Fluor 488 NBP2-47720AF488
Alexa Fluor 532 NBP2-47720AF532
Alexa Fluor 594 NBP2-47720AF594
Alexa Fluor 647 NBP2-47720AF647
Alexa Fluor 700 NBP2-47720AF700
Alexa Fluor 750 NBP2-47720AF750
Allophycocyanin NBP2-47720APC
Biotin NBP2-47720B
DyLight 350 NBP2-47720UV
DyLight 405 NBP2-47720V
DyLight 488 NBP2-47720G
DyLight 550 NBP2-47720R
DyLight 594 NBP2-47720DL594
DyLight 650 NBP2-47720C
DyLight 680 NBP2-47720FR
DyLight 755 NBP2-47720IR
FITC NBP2-47720F
HRP NBP2-47720H
Janelia Fluor 549 NBP2-47720JF549
Janelia Fluor 646 NBP2-47720JF646
PE NBP2-47720PE
PerCP NBP2-47720PCP

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol KRT14