Cytokeratin 14 Products

Antibodies
Cytokeratin 14 Antibody
Cytokeratin 14 Antibody
NBP1-31326
Species: Hu, Rt, Bovine, Canine, Mouse
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Lysates
Cytokeratin 14 Overexpression ...
Cytokeratin 14 Overexpression Lysa...
NBL1-12381
Applications: WB
Cytokeratin 14 Overexpression ...
Cytokeratin 14 Overexpression Lysa...
H00003861-T02
Applications: WB
Proteins
Cytokeratin 14 Recombinant Pr ...
Cytokeratin 14 Recombinant Protein...
NBP1-84917PEP
Species: Hu
Applications: AC
Cytokeratin 14 Recombinant Pr ...
Cytokeratin 14 Recombinant Protein
NBP1-72467
Species: Hu
Applications: PAGE

Description

Keratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. Cytokeratin 14 (CK-14) is a 50-kDa keratin expressed in abundance in human epidermal cells (1). During anagen, cell proliferation in the germinative matrix of the hair follicle gives rise to the fiber and inner root sheath. The transition from anagen to telogen is marked by downregulation of hair cortical specific keratins and the appearance of CK-14 in the epithelial sac to which the telogen hair fiber is anchored (2). A family with recessive epidermolysis bullosa simplex lacked expression of the basal cell keratin 14. The patients had severe generalized skin blistering that improved slightly with age. The basal cells of the patients did not express keratin 14 and contained no keratin intermediate filaments. The expression of keratin 5, the obligate copolymer of keratin 14, was slightly reduced (3).

Bioinformatics

Entrez Human
Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 3861
Alternate Names
  • Keratin-14
  • EBS4
  • Cytokeratin-14
  • EBS3
  • keratin-14
  • CK14
  • keratin, type I cytoskeletal 14
  • K14
  • cytokeratin-14
  • CK-14
  • cytokeratin 14
  • keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)
  • NFJ
  • keratin 14

Research Areas for Cytokeratin 14

Find related products by research area and learn more about each of the different research areas below.

Cytoskeleton Markers

PTMs for Cytokeratin 14

Learn more about PTMs related to Cytokeratin 14.

Phosphorylation
Ubiquitination

Bioinformatics Tool for Cytokeratin 14

Discover related pathways, diseases and genes to Cytokeratin 14. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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