Cytochrome P450 2C8 Antibody

Images

 
Western Blot: Cytochrome P450 2C8 Antibody [NBP1-97759] - (0.1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Concentration
0.5 mg/ml

Order Details

Cytochrome P450 2C8 Antibody Summary

Immunogen
Peptide with sequence C-KNVALTRSYIREK corresponding to internal region according to NP_000761.3, NP_001185782.1, NP_001185783.1.
Specificity
This antibody is expected to recognize all reported isoforms (NP_000761.3; NP_001185782.1; NP_001185783.1). No cross-reactivity with other 2C proteins expected. Reported variants represent identical protein: NP_001185782.1, NP_001185784.1
Clonality
Polyclonal
Host
Goat
Gene
CYP2C8
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Conjugate
Unconjugated
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.3 ug/ml
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx. 55 kDa band observed in human liver lysates (calculated MW of 55.8 kDa band according to NP_000761.3).
Publications
Read Publication using NBP1-97759.

Alternate Names for Cytochrome P450 2C8 Antibody

  • CPC8
  • CYPIIC8
  • cytochrome P450 2C8
  • Cytochrome P450 form 1
  • Cytochrome P450 IIC2
  • Cytochrome P450 MP-12
  • Cytochrome P450 MP-20
  • cytochrome P450, family 2, subfamily C, polypeptide 8
  • cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8
  • EC 1.14.14.1
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • MP-12/MP-20
  • P450 form 1
  • S-mephenytoin 4-hydroxylase
  • xenobiotic monooxygenase

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cytochrome P450 2C8 Antibody (NBP1-97759)(1)

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol CYP2C8
Entrez
Uniprot

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