Cytochrome P450 1A2 Antibody (F16 P2 D8) - BSA Free

Western Blot: Cytochrome P450 1A2 Antibody (F16 P2 D8) [NBP3-11912] - Left: Western blot using CYP2A6 antibody on recombinant cytochrome p450 at 1 ug/ml. Right: Staining using CYP2A6 antibody on normal human liver tissue at 1 ug/ml.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clone: F16 P2 D8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Cytochrome P450 1A2 Antibody (F16 P2 D8) - BSA Free Summary

• Description: Novus Biologicals Mouse Cytochrome P450 1A2 Antibody (F16 P2 D8) - BSA Free (NBP3-11912) is a monoclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with Synthetic peptide conjugated to ovalbumin derived from the C-terminus of CYP2A6 and mouse myeloma Ag8563 cells. Antigen identical in CYP2A6, 2A7 and 2A13. (Uniprot: P05177)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CYP1A2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot 1 - 2 ug/ml
• Application Notes: ELISA titer to be determined by end-user..

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.08% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for Cytochrome P450 1A2 Antibody (F16 P2 D8) - BSA Free

• aryl hydrocarbon hydroxylase
• CP12
• CYP1A2
• CYPIA2
• Cytochrome P(3)450
• Cytochrome P450 1A2
• Cytochrome P450 4
• cytochrome P450, family 1, subfamily A, polypeptide 2
• cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2
• Cytochrome P450-P3
• dioxin-inducible P3-450
• EC 1.14.14.1
• flavoprotein-linked monooxygenase
• microsomal monooxygenase
• P3-450
• P450 form 4
• P450(PA)
• xenobiotic monooxygenase

Background

In animals, P450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. CYP1A2 is an aryl hydrocarbon hydroxylase involved in the metabolism of endogenous compounds and xenobiotics. It is one of the major drug metabolising enzymes in humans.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CYP1A2
• Uniprot:
  • P05177(Human)