Cytochrome P450 1A2 Products

Description

In animals, P450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. CYP1A2 is an aryl hydrocarbon hydroxylase involved in the metabolism of endogenous compounds and xenobiotics. It is one of the major drug metabolising enzymes in humans.

Bioinformatics

Entrez	1544 Human 13077 Mouse 24297 Rat
Uniprot	NP_000752 Human P05177 Human AAH67427.1 Human
Product By Gene ID	1544
Alternate Names	EC 1.14.14.1 xenobiotic monooxygenase CYPIA2 P450 form 4 Cytochrome P450-P3 microsomal monooxygenase Cytochrome P450 4 flavoprotein-linked monooxygenase Cytochrome P(3)450 dioxin-inducible P3-450 cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2 cytochrome P450 1A2 P3-450 aryl hydrocarbon hydroxylase CP12 P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2

Diseases related to Cytochrome P450 1A2

Discover more about diseases related to Cytochrome P450 1A2.

Malignant Neoplasms
Neoplasms
Carcinogenesis
Liver Carcinoma
Hepatotoxicity
Malignant Neoplasm Of Breast
Carcinoma
Schizophrenia
Depressive Disorder
Liver Diseases
Mammary Neoplasms
Liver Neoplasms
Salmonella Infections
Hepatitis
Inflammation
Colorectal Cancer
Injury To Liver
Liver Neoplasms, Experimental

Pathways for Cytochrome P450 1A2

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Excretion
Demethylation
Conjugation
Transport
Localization
Cell Proliferation
Secretion
Pathogenesis
Reverse Transcription
Cell Cycle
Dna Repair
Sulfation
Methylation
Cell Death
Lactation
Platelet Aggregation
Translation
Glomerular Filtration
Aging
Regeneration

Research Areas for Cytochrome P450 1A2

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Cancer
Lipid and Metabolism

PTMs for Cytochrome P450 1A2

Learn more about PTMs related to Cytochrome P450 1A2.

Hydroxylation
Demethylation
Oxidation
Acetylation
Reduction
Phosphorylation
Methylation
Nitration
Cleavage
Sulphation
Carboxylation
Phosphorothioation
Deamination
Glycosylation
Dephosphorylation
Prenylation
Bromination
Ubiquitination
Biotinylation
Deacetylation

Bioinformatics Tool for Cytochrome P450 1A2

Discover related pathways, diseases and genes to Cytochrome P450 1A2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.