Cytochrome P450 1A1 Antibody

Images

 
Western Blot: Cytochrome P450 1A1 Antibody [H00001543-D01P] - Analysis of CYP1A1 expression in transfected 293T cell line by CYP1A1 polyclonal antibody.Lane 1: CYP1A1 transfected lysate(58.20 KDa).Lane 2: ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Cytochrome P450 1A1 Antibody Summary

Immunogen
CYP1A1 (NP_000490.1, 1 a.a. - 512 a.a.) full-length human protein. MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS
Specificity
Reacts with cytochrome P450, family 1, subfamily A, polypeptide 1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CYP1A1
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cytochrome P450 1A1 Antibody

  • AHH
  • AHRR
  • aryl hydrocarbon hydroxylase
  • CP11
  • CYP1
  • CYPIA1
  • cytochrome P1-450, dioxin-inducible
  • cytochrome P450 1A1
  • Cytochrome P450 form 6
  • cytochrome P450, family 1, subfamily A, polypeptide 1
  • Cytochrome P450-C
  • Cytochrome P450-P1
  • EC 1.14.14.1
  • flavoprotein-linked monooxygenase
  • P1-450
  • P450-C
  • P450DX
  • subfamily I (aromatic compound-inducible), polypeptide 1
  • xenobiotic monooxygenase

Background

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CYP1A1
Entrez
Uniprot