Cytochrome P450 1A1 Products

Description

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

Bioinformatics

Entrez	1543 Human
Uniprot	NP_000490.1 Human
Product By Gene ID	1543
Alternate Names	AHH AHRR aryl hydrocarbon hydroxylase CP11 CYP1 CYP1A1 CYPIA1 cytochrome P1-450, dioxin-inducible Cytochrome P450 1A1 Cytochrome P450 form 6 cytochrome P450, family 1, subfamily A, polypeptide 1 Cytochrome P450-C Cytochrome P450-P1 EC 1.14.14.1 flavoprotein-linked monooxygenase P1-450 P450-C P450DX subfamily I (aromatic compound-inducible), polypeptide 1 xenobiotic monooxygenase

Research Areas for Cytochrome P450 1A1

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Lipid and Metabolism