Cysteinyl Leukotriene R1/CysLTR1 Antibody

Images

 
Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NLS1320] - Analysis of anti-CYSLTR1 / CYSLT1 antibody with human lymph node, Hodgkins lymphoma.
Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NLS1320] - Staining of human nasal mucosa, allergic rhinitis, eosinophils after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Mu, Mk, PmSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Cysteinyl Leukotriene R1/CysLTR1 Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from C-terminus of human CYSLTR1 / CYSLT1.
Localization
Integral membrane protein
Specificity
Human CYSLTR1 / CYSLT1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BRCA1 (45%).
Predicted Species
Mouse (90%), Monkey (95%), Primate (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CYSLTR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10 - 1:500

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (95%), Gibbon (90%), Panda (90%), Rat (85%), Bovine (85%), Elephant (85%), Rabbit (85%), Porcine (85%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Cysteinyl Leukotriene R1/CysLTR1 Antibody

  • CysLT(1)
  • CysLT1
  • CYSLT1CysLT1
  • CYSLT1R
  • CYSLTR
  • CysLTR1
  • Cysteinyl leukotriene D4 receptor
  • Cysteinyl Leukotriene R1
  • cysteinyl leukotriene receptor 1
  • Cysteinyl LeukotrieneR1
  • G-protein coupled receptor HG55
  • HG55
  • HMTMF81
  • LTD4 Receptor
  • MGC46139

Background

Cysteinyl leukotriene receptor 1, a Chemoattractant Receptor, is detected in spleen, peripheral blood leukocytes, and lung smooth muscle (Lynch et al., 1999). It binds cysteinyl leukotrienes, which are neutrophil chemoattractants with potent proinflammatory action. Leukotrienes mediate many features of bronchial asthma such as edema, bronchial constriction, and hyperreactivity (Bisgaard et al., 2000). Selective CysLT1 antagonists are used to treat asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CYSLTR1
Entrez
Uniprot