Cysteinyl Leukotriene R1/CysLTR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NLS1320] - Analysis of anti-CYSLTR1 / CYSLT1 antibody with human lymph node, Hodgkins lymphoma.

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R1/CysLTR1 Antibody [NLS1320] - Staining of human nasal mucosa, allergic rhinitis, eosinophils after heat-induced antigen retrieval.

• Reactivity: Hu, Mu, Pm, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Cysteinyl Leukotriene R1/CysLTR1 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 20 amino acid peptide from C-terminus of human Cysteinyl Leukotriene R1/CysLTR1.
• Epitope: C-Terminus
• Localization: Integral membrane protein
• Specificity: Human Cysteinyl Leukotriene R1/CysLTR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BRCA1 (45%).
• Predicted Species: Mouse (90%), Primate (100%), Monkey (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CYSLTR1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 9-22 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (95%), Gibbon (90%), Rat (85%), Bovine (85%), Rabbit (85%), Porcine (85%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Cysteinyl Leukotriene R1/CysLTR1 Antibody - BSA Free

• CysLT(1)
• CysLT1
• CYSLT1CysLT1
• CYSLT1R
• CYSLTR
• CysLTR1
• Cysteinyl leukotriene D4 receptor
• Cysteinyl Leukotriene R1
• cysteinyl leukotriene receptor 1
• Cysteinyl LeukotrieneR1
• G-protein coupled receptor HG55
• HG55
• HMTMF81
• LTD4 Receptor
• MGC46139

Background

Cysteinyl leukotriene receptor 1, a Chemoattractant Receptor, is detected in spleen, peripheral blood leukocytes, and lung smooth muscle (Lynch et al., 1999). It binds cysteinyl leukotrienes, which are neutrophil chemoattractants with potent proinflammatory action. Leukotrienes mediate many features of bronchial asthma such as edema, bronchial constriction, and hyperreactivity (Bisgaard et al., 2000). Selective CysLT1 antagonists are used to treat asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CYSLTR1
• Entrez:
  • 10800(Human)
• Uniprot:
  • Q9Y271(Human)