Cystatin D/Cst5 Antibody (206006) [DyLight 405]

• Reactivity: Hu
• Applications: WB, IP, B/N
• Clone: 206006
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 405

Cystatin D/Cst5 Antibody (206006) [DyLight 405] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Cystatin D
  Arg28-Val142
  Accession # P28325
• Specificity: Detects human Cystatin D in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human (rh) Cystatins A, B, C, E/M, S, SA, SN, rhKininogen, rhFetuins A, B, or rhHPRG is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: CST5
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Neutralization
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Cystatin D/Cst5 Antibody (206006) [DyLight 405]

• CST5
• CSTD
• cystatin 5
• Cystatin D
• Cystatin-5
• cystatin-D
• cysteine-proteinase inhibitor
• MGC71922

Background

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CST5