CYP4B1 Antibody

Western Blot: CYP4B1 Antibody [NBP2-16068] - Sample (30 ug of whole cell lysate) A: A549 B: H1299 C: MCF-7 7. 5% SDS PAGE gel, diluted at 1:5000.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

CYP4B1 Antibody Summary

• Description: Novus Biologicals Rabbit CYP4B1 Antibody (NBP2-16068) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human CYP4B1. The exact sequence is proprietary.
• Localization: Endoplasmic reticulum membrane; Microsome membrane
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CYP4B1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000-1:10000
• Theoretical MW: 59 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rabbit (85%), Rat (88%), Bovine (83%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for CYP4B1 Antibody

• CYPIVB1
• cytochrome P450 4B1
• cytochrome P450, family 4, subfamily B, polypeptide 1
• cytochrome P450, subfamily IVB, polypeptide 1
• Cytochrome P450-HP
• EC 1.14.14.1
• microsomal monooxygenase
• P-450HP

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: CYP4B1
• Uniprot:
  • P13584(Human)