CYP46A1 Antibody (1A11) - Azide and BSA Free

Sandwich ELISA: CYP46A1 Antibody (1A11) [H00010858-M01] - Detection limit for recombinant GST tagged CYP46A1 is approximately 0.03ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 1A11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

CYP46A1 Antibody (1A11) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse CYP46A1 Antibody (1A11) - Azide and BSA Free (H00010858-M01) is a monoclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: CYP46A1 (NP_006659, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVTFF
• Specificity: CYP46A1 - cytochrome P450, family 46, subfamily A, polypeptide 1
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CYP46A1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CYP46A1 Antibody (1A11) - Azide and BSA Free

• CH24H
• cholesterol 24-hydroxylase
• CYP46CP46
• Cytochrome P450 46A1
• cytochrome P450, family 46, subfamily A, polypeptide 1
• cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
• EC 1.14.13.98

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CYP46A1
• Entrez:
  • 10858(Human)
• OMIM:
  • 604087(Human)
• Uniprot:
  • NP_006659(Human)