CXCL3/GRO gamma/CINC-2/DCIP-1 Antibody [Unconjugated]

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Recombinant Rat CXCL3/CINC‑2 alpha (Catalog # 516‑CA) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CXCR2 in a dose-dependent manner (orange line). The amount of cells that migrated through ...read more

Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, B/N
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Conjugate Size Price
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Catalog# & Formulation Size Price

CXCL3/GRO gamma/CINC-2/DCIP-1 Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant rat CXCL3/CINC-2 alpha / beta
Arg33-Ser100
Accession # Q10746
Specificity
Detects rat CXCL3/CINC-2 alpha / beta in direct ELISAs and Western blots. In direct ELISAs, greater than 50% cross-reactivity with recombinant rat (rr) CINC-1, rrCINC-2 beta, and rrCINC-3 is observed, less than 25% cross-reactivity with recombinant mouse (rm) KC, rmMIP-2, recombinant human (rh) GRO alpha, rhGRO beta, and rhGRO gamma is observed, and less than 10% cross-reactivity with rhIL-8 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
Cxcl3
Purity Statement
Antigen Affinity-purified
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
  • Neutralization 0.5-2.0 ug/mL
Publications
Read Publication using
AF516 in the following applications:

  • ICC
    1 publication

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CXCL3/GRO gamma/CINC-2/DCIP-1 Antibody [Unconjugated]

  • chemokine (C-X-C motif) ligand 3
  • CINC-2
  • CINC-2b
  • C-X-C motif chemokine 3
  • CXCL3
  • Dcip1
  • Gm1960
  • GRO gamma
  • GRO3 oncogene
  • GRO3
  • GROG
  • GRO-gamma
  • GRO-gamma(1-73)
  • Growth-regulated protein gamma
  • Macrophage inflammatory protein 2-beta
  • melanoma growth stimulatory activity gamma
  • MGSA gamma
  • MIP2B
  • MIP-2b
  • MIP2-beta
  • SCYB3

Background

CINC-2 alpha and -2 beta are mRNA splice variant isoforms that differ by only 3 amino acids at their amino-termini. These proteins are CXC chemokines most closely related to human GROs and mouse MIP-2. They are produced by granulation tissue, activated macrophages and fibroblasts. CINC-2 biological activities are mediated by CXCR1 or CXCR2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, B/N

Publications for CXCL3/GRO gamma/CINC-2/DCIP-1 Antibody (AF516)(1)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: ICC.


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ICC
(1)
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Rat
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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin BAF516

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Bioinformatics

Gene Symbol Cxcl3
Uniprot