Mouse CXCL16 Protein Summary
A biologically active protein to CXCL16.
Source: E. coli
Amino Acid Sequence: NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQWVRELVDCFER KECGTGHGKS FHHQKHLP
Novus' biologically active proteins are stringently purified to provide only the safest and most highly effective proteins available. This protein was expressed in E. coli, purified by HPLC, QC tested by SDS-PAGE and Western Blot and validated on appropriate cell lines for bioactivity. All HPLC and bioactivity data is provided for your assurance.
|Details of Functionality
CXCL16 Protein is fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine lymphocytes is in a concentration of 20-1000 ng/ml.
Size Exclusion Chromatography
Less than 1 EU/ug of endotoxin as determined by LAL method.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Size Exclusion Chromatography
Reconstitute with sterilized distilled water or 0.1% BSA aqueous buffer to a final concentration of 0.1 - 1.0 mg/ml.
This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.
Alternate Names for Mouse CXCL16 Protein
- chemokine (C-X-C motif) ligand 16
- CXC chemokine ligand 16
- Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
- Small-inducible cytokine B16
- SRPSOXC-X-C motif chemokine 16
- SR-PSOXTransmembrane chemokine CXCL16
CXCL16 is a member of the CXC chemokine family. Larger than other chemokines, it is one of the only two transmembrane chemokines in the family and the other is CX3CL1. Mouse CXCL16 has 246 a.a. and consists of a 26 a.a. residue putative signal peptide, an 88 a.a. residue chemokine domain, an 87 a.a. residue mucin-like spacer region, a 22 a.a. residue transmembrane domain, and a 23 a.a. residue cytoplasmic tail. Mouse CXCL16 shares 70 % sequence identity with human CXCL16 in chemokine domain. CXCL16 interacts with the chemokine receptor CXCR6, also known as Bonzo. Expression of CXCL16 is induced by the inflammatory cytokines IFN-gamma and TNF-alpha. Functions of CXCL16 include inducing a strong chemotactic response and calcium mobilization. CXCL16 also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 2 years from date of receipt.
Customers Who Viewed This Item Also Viewed...
Applications: WB, IHC, Neut
Applications: ELISA(Cap), ELISA(Det), Neut, ELISA(Sta)
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, InhibTFunc
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Applications: WB, Neut
Applications: Flow, IHC, Neut
Applications: Func, PAGE
Publications for CXCL16 Protein (NBP2-35166) (0)
There are no publications for CXCL16 Protein (NBP2-35166).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for CXCL16 Protein (NBP2-35166) (0)
There are no reviews for CXCL16 Protein (NBP2-35166).
By submitting a review earn points towards our Rewards Program.
- 250 points for product review
- 500 additional points for an image with your product review
- Double points (500) if you are the first to review this product
- Double points (1000) if you are the first to review this product with an image
FAQs for CXCL16 Protein (NBP2-35166) (0)
Additional Mouse CXCL16 Protein Products
Related Products by Gene
Bioinformatics Tool for CXCL16 Protein (NBP2-35166)
Discover related pathways, diseases and genes to CXCL16 Protein (NBP2-35166). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on CXCL16