CTRP9/C1qTNF9 Antibody (653533) [Unconjugated]

• Reactivity: Hu
• Applications: WB
• Clone: 653533
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

CTRP9/C1qTNF9 Antibody (653533) [Unconjugated] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human CTRP9/C1qTNF9
  Asn16-Pro333
  Accession # P0C862
• Specificity: Detects human CTRP9/C1qTNF9 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) C1qTNF1, rhCORS26/C1qTNF3, rhC1qTNF4, rhC1qTNF5, rhC1QL2 is observed.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: C1QTNF9
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CTRP9/C1qTNF9 Antibody (653533) [Unconjugated]

• AQL1
• C1q and tumor necrosis factor related protein 9
• C1qTNF9
• C1QTNF9AComplement C1q tumor necrosis factor-related protein 9
• complement C1q tumor necrosis factor-related protein 9A
• CTRP9
• MGC48915

Background

C1qTNF9, also known as CTRP9, is one of several Adiponectin/Acrp30 paralogs which comprise the C1q and TNF-related protein family. All family members share a modular organization comprising a short variable region, a collagenous domain, and a C1q-like globular domain. C1qTNF9 is a 40 kDa glycoprotein that contains multiple hydroxylated proline residues in its collagenous region. It circulates as a homotrimer and higher order multimers as well as in heterotrimers with Adiponectin. It is preferentially expressed in adipose tissue and plays a role in glucose homeostasis. Human C1qTNF9 shares 85% amino acid sequence identity with mouse and rat C1qTNF9.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CTRP9/C1qTNF9 Antibody (MAB6537)(1)

Publication using MAB6537

• R Haustein, FA Trogisch, M Keles, S Hille, M Fuhrmann, N Weinzierl, S Hemanna, J Thackeray, Y Dou, C Zwadlo, N Froese, J Cordero, F Bengel, OJ Müller, J Bauersachs, G Dobreva, J Heineke C1q and Tumor Necrosis Factor Related Protein 9 Protects from Diabetic Cardiomyopathy by Alleviating Cardiac Insulin Resistance and Inflammation Cells, 2023-01-29;12(3):. 2023-01-29 [PMID: 36766785]

Bioinformatics

• Gene Symbol: C1QTNF9
• Uniprot:
  • P0C862()