CRX/CORD2 Antibody - BSA Free

Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88059] - Staining of human testis.

Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88059] - Staining of human retina shows strong nuclear positivity in photoreceptor cells.

Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88059] - Staining of human colon shows no positivity in glandular cells as expected.

Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88059] - Staining of human eye, retina.

Immunohistochemistry-Paraffin: CRX/CORD2 Antibody [NBP1-88059] - Staining of human cerebral cortex.

Staining of human colon using Anti-CRX antibody HPA036763.

Analysis in control (vector only transfected HEK293T lysate) and CRX over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells).

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CRX/CORD2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CRX/CORD2 Antibody - BSA Free (NBP1-88059) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: KARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSI
• Predicted Species: Mouse (96%), Rat (96%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CRX
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  CRX/CORD2 Protein (NBP1-88059PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for CRX/CORD2 Antibody - BSA Free

• cone-rod homeobox
• CORD2
• CRDcone-rod homeobox protein
• CRX
• LCA7
• LCA7orthodenticle homeobox 3
• OTX3

Background

CORD2 is encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CRX