CREBL2 Antibody (1C1) - Azide and BSA Free

Western Blot: CREBL2 Antibody (1C1) [H00001389-M04] - Analysis of CREBL2 expression in transfected 293T cell line by CREBL2 monoclonal antibody (M04), clone 1C1. Lane 1: CREBL2 transfected lysate (Predicted MW: 13.8 KDa). Lane 2: Non-transfected lysate.

Sandwich ELISA: CREBL2 Antibody (1C1) [H00001389-M04] - Detection limit for recombinant GST tagged CREBL2 is 1 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 1C1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

CREBL2 Antibody (1C1) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: CREBL2 (NP_001301.1, 1 a.a. ~ 120 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MDDSKVVGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIKALLTGEEQNKSQQNSSRHTKAGKTDANSNSW
• Specificity: This product is specific for Human CREBL2 monoclonal antibody (M04), clone 1C1 [Gene ID: 1389].
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CREBL2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CREBL2 Antibody (1C1) - Azide and BSA Free

• cAMP responsive element binding protein-like 2
• cAMP-responsive element-binding protein-like 2
• MGC117311
• MGC138362

Background

cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonlydeleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoieticmalignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity withCRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consistsof about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved inprotein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance ofCREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CREBL2
• Uniprot:
  • NP_001301.1(Human)